Glucuronidation patterns of common urinary and serum monoester phthalate metabolites
نویسندگان
چکیده
منابع مشابه
DNA damage in human sperm is related to urinary levels of phthalate monoester and oxidative metabolites.
BACKGROUND The ubiquitous use of phthalate esters in plastics, personal care products and food packaging materials results in widespread general population exposure. In this report, we extend our preliminary study on the relationship between urinary concentrations of phthalate metabolites and sperm DNA damage among a larger sample of men and include measurements of mono-(2-ethyl-5-hydroxyhexyl)...
متن کاملAltered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites.
BACKGROUND Phthalates are multifunctional chemicals used in a variety of consumer, medical, and personal care products. Previously, we reported dose-response associations of decreased semen quality with urinary concentrations of monobutyl phthalate (MBP) and monobenzyl (MBzP) phthalate, which are metabolites of dibutyl phthalate and butylbenzyl phthalate, respectively. The present study extends...
متن کاملCharacterization of Urinary Phthalate Metabolites Among Custodians.
Phthalates, a ubiquitous class of chemicals found in consumer, personal care, and cleaning products, have been linked to adverse health effects. Our goal was to characterize urinary phthalate metabolite concentrations and to identify work and nonwork sources among custodians using traditional cleaning chemicals and 'green' or environmentally preferable products (EPP). Sixty-eight custodians pro...
متن کاملComparisons of urinary phthalate metabolites and daily phthalate intakes among Japanese families.
We measured urinary phthalate metabolites, including di-n-butyl phthalate (DnBP), di-isobutyl phthalate, benzyl butyl phthalate (BBzP), and di(2-ethylhexyl) phthalate (DEHP), from 178 school-aged children and their 284 family members using gas chromatography-mass spectrometry, and we calculated daily phthalate intakes. The highest median levels of phthalate metabolites were for mono-isobutyl ph...
متن کاملReproducibility of urinary phthalate metabolites in first morning urine samples.
Phthalates are ubiquitous in our modern environment because of their use in plastics and cosmetic products. Phthalate monoesters--primarily monoethylhexyl phthalate and monobutyl phthalate--are reproductive and developmental toxicants in animals. Accurate measures of phthalate exposure are needed to assess their human health effects. Phthalate monoesters have a biologic half-life of approximate...
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ژورنال
عنوان ژورنال: Archives of Toxicology
سال: 2005
ISSN: 0340-5761,1432-0738
DOI: 10.1007/s00204-005-0653-9